Publications
Our work
Selected publications from the Stevens Lab and prior training.
2023Featured
Programming multicellular assembly with synthetic cell adhesion molecules
Stevens AJ, Harris AR, Gerdts J, Kim KH, Trentesaux C, Ramirez JT, McKeithan WL, Fattahi F, Klein OD, Fletcher DA, Lim WA.
Nature 614, 144–152View paper →
2025
Synthetic organizer cells guide development via spatial and biochemical instructions
Yamada T, Trentesaux C, Brunger JM, Xiao Y, Stevens AJ, Martyn I, Kasparek P, Shroff NP, Aguilar A, Bruneau BG, et al.
Cell 188, 1–18View paper →
2022
A conserved histidine residue drives extein dependence in an enhanced atypically split intein
Sekar G, Stevens AJ, Mostafavi AZ, Sashi P, Muir TW, Cowburn D.
J. Am. Chem. Soc. 144, 17955–17966View paper →
2020
Identification, characterization, and optimization of split inteins
Stevens AJ.
Methods in Molecular Biology vol. 2133View paper →
2019
Protein engineering through tandem transamidation
Stevens AJ, et al.
Nature Chemistry 11, 1009–1016View paper →
2018
An atypical mechanism of split intein molecular recognition and folding
Stevens AJ*, Sekar G*, Gramespacher JA, Cowburn D, Muir TW.
J. Am. Chem. Soc. 140, 11791–11799View paper →
2018
Improved protein splicing using embedded split inteins
Gramespacher JA, Stevens AJ, Thompson RE, Muir TW.
Protein Science 27, 614–619View paper →
2017
A promiscuous split intein with expanded protein engineering applications
Stevens AJ, Sekar G, Shah NH, Mostafavi AZ, Cowburn D, Muir TW.
Proc. Natl. Acad. Sci. 114, 8538–8543View paper →
2017
Intein zymogens: conditional assembly and splicing of split inteins via targeted proteolysis
Gramespacher JA, Stevens AJ, Nguyen DP, Chin JW, Muir TW.
J. Am. Chem. Soc. 139, 8074–8077View paper →
2016
Design of a split intein with exceptional protein splicing activity
Stevens AJ, Brown ZZ, Shah NH, Sekar G, Cowburn D, Muir TW.
J. Am. Chem. Soc. 138, 2162–2165View paper →
2013
DNA polymerase λ inactivation by oxidized abasic sites
Stevens AJ, Guan L, Bebenek K, Kunkel TA, Greenberg MM.
Biochemistry 52, 975–983View paper →